Associations of Particulate Matter Sizes and Chemical Constituents with Blood Lipids: A Panel Study in Guangzhou, China

Existing evidence is scarce concerning the various effects of different PM sizes and chemical constituents on blood lipids. A panel study that involved 88 healthy college students with five repeated measurements (440 samples in total) was performed. We measured mass concentrations particulate matter diameters ≤ 2.5 μm (PM2.5), ≤1.0 (PM1.0), ≤0.5 (PM0.5) as well number 0.2 (PN0.2) ≤0.1 (PN0.1). applied linear mixed-effect models to assess associations between short-term exposure size fractions PM2.5 seven lipid metrics. found significant greater within 5 days before collection lower high-density lipoprotein cholesterol (HDL-C) apolipoprotein (ApoA1) levels, higher B (ApoB) ApoA1/ApoB ratios. Among constituents, we observed tin lead were significantly associated decreased HDL-C nickel levels. Our results suggest deleteriously Some especially metals, might be major contributors detrimental effects.